A free NOAA center on the Florida Keys National Marine Sanctuary.
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A 19th-century coastal fort on Garden Key, 70 miles west of Key West.
The Oldest House Museum, built in 1829, is the oldest surviving house in South Florida.
The Key West Shipwreck Museum tells the story of the island's wrecking industry, with artifacts from the 1856 wreck of the Isaac Allerton.
The Waterfront Playhouse, near Mallory Square, is one of Key West's oldest community theaters.

Tropic Cinema is Key West's nonprofit independent cinema.
The Studios of Key West is an arts center with galleries, artist residencies and classes in the historic Armory.
The Tennessee Williams Theatre at the College of the Florida Keys is Key West's largest performing arts venue.
The Red Barn Theatre is an intimate professional theater behind Duval Street in a historic carriage house.

The Key West Library is the oldest public library in South Florida, serving the island since 1892.
The Little White House was President Harry S. Truman's winter White House.
Fort Zachary Taylor is a pre-Civil War fort and National Historic Landmark.
The Ernest Hemingway Home and Museum is where the author lived and wrote in the 1930s.
The Mel Fisher Maritime Museum displays treasure and artifacts from the Atocha and other wrecks.
The Key West Tropical Forest & Botanical Garden is the only frost-free botanical garden in the continental US.
The Key West Museum of Art & History is in the restored 1891 Custom House.
The Key West Lighthouse, first lit in 1848, is run as a museum by the Key West Art & Historical Society.
Fort East Martello is a Civil War-era fort turned museum, home of Robert the Doll.